The 2024 San Antonio Breast Cancer Symposium^® is fully underway today, in person at the Henry B. Gonzalez Convention Center and worldwide for virtual registrants. Each morning, SABCS Meeting News is providing a rundown of what you need to know for the day ahead.

A packed scientific program awaits, but today also marks the opening of the SABCS^® Exhibit Hall, directly across from the main lobby entrance in Halls 2-3. From 12 to 7 p.m. CT, visitors can interact with a record number of exhibiting companies and organizations, attend Product Theater presentations, view poster abstracts, and check out new amenities, including the SABCS^® Networking Hub, the SABCS^® Culinary Corner supported by H-E-B, and the Patient Advocacy Pavilion supported by Pfizer. Light refreshments will be served in the poster area, along the left and back walls, during two Poster Sessions, from 12:30 to 2 p.m. and again from 5:30 to 7 p.m.

Also, don’t forget to take part in the SABCS^® Duck Pluck fundraiser for early-career scientists. Stop by the SABCS^® Store in the main lobby before 11 a.m. on Thursday to grab a duck and try your luck at prizes.

Now, here are your program highlights for Wednesday, December 11, 2024.

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(Full session details can be found in the SABCS® 2024 app, virtual platform, and on SABCS.org.)

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Poster Spotlight Sessions

Learn about top-rated abstracts during five sessions occurring concurrently from 7 to 8:30 a.m.

These moderated sessions will each present eight to nine posters on important topics across the breast cancer landscape. Thirty minutes of poster viewing will be followed by two discussion and panel Q&A periods, each addressing a common theme shared by half of the session’s abstracts. Today’s topics include:

• Session 1: New Insights into Immune Biomarkers (Room 221ABC)
• Session 3: Highlights on Novel Therapeutics (Stars at Night 1-2)
• Session 4: Prediction of Chemotherapy Response (Stars at Night 3-4)
• Session 5: The Heart of the Matter – Improving Adverse Effects (Hemisfair Ballroom 3)
• Session 7: Targeting the ER and PI3K pathway: Novel drugs and combinations (Hemisfair Ballroom 1-2)

Opening Session

A full morning of illuminating lectures and scientific presentations in Hall 1, just off the main lobby, will begin at 8:30 a.m.

SABCS^® Co-Directors Virginia G. Kaklamani, MD, and Carlos L. Arteaga, MD, will officially welcome attendees to the Symposium and introduce 2019 Nobel Prize winner William G. Kaelin, Jr., MD, who will deliver the 2024 Keynote Address. The first General Session, featuring clinical trial results with the potential to reshape practice, will follow, and after that, Laura J. van ‘t Veer, PhD, will present the 2024 William L. McGuire Memorial Lecture.

• Welcome and Opening Remarks (8:30 a.m.)
• Keynote Address: (Re)emerging Principles for Controlling Cancer with Drugs (8:35 to 9:15 a.m.)
• General Session 1 (9:15 to 11:30 a.m.)
• William L. McGuire Memorial Lecture (11:30 a.m. to noon)

Featured speakers and afternoon sessions

This afternoon’s schedule is filled with even more featured speakers. Anne C. Welsh, PhD, ACC, and Reshma Jagsi, MD, DPhil, will share insights in the annual women’s career development workshop from 1 to 3:30 p.m., and Christina Curtis, PhD, MSc, will deliver an American Association for Cancer Research (AACR) award lecture from 3 to 3:30 p.m.

• Navigating Success: Women’s Career Development (Room 221ABC)
• AACR Outstanding Investigator Award for Breast Cancer Research (Stars at Night 1-2)

In addition, attendees will have their choice of rapid-fire oral presentations, case studies, panel discussions, and educational sessions, including the annual People’s Choice session. Open the SABCS^® app and virtual platform for full details, and check back after the sessions to watch on-demand recordings of anything you’ve missed.

• Rapid Fire 1 (12 to 12:50 p.m., Hall 1)
• Risk Reduction and Early Detection: Updates on Breast Cancer Screening (12 to 1:45 p.m., Stars at Night 3-4)
• Clinical Case Discussions (1 to 1:50 p.m., Stars at Night 1-2)
• State of the Art Session 1: The Winding Road of Immune Biomarkers in Early Breast Cancer (2 to 3 p.m., Stars at Night 3-4)
• Translational Controversies (2 to 3 p.m., Stars at Night 1-2)
• Educational Session 5: Unlocking New Targets with Molecular Degraders (3:30 to 5:15 p.m., Hemisfair Ballroom 3)
• Educational Session 6: Case-Based Clinical Approach to ER-Positive Metastatic Breast Cancer – In honor of Dr. V. Craig Jordan (3:30 to 5:15 p.m., Stars at Night 1-2)
• Educational Session 7: People’s Choice – Future Directions in Antibody-Drug Conjugates (3:30 to 5:15 p.m., Hemisfair Ballroom 1-2)
• Educational Session 8: Optimizing Local Therapy (3:30 to 5:15 p.m., Stars at Night 3-4)