The 2024 San Antonio Breast Cancer Symposium^® continues today in person at the Henry B. Gonzalez Convention Center and worldwide for virtual registrants. Each morning, SABCS Meeting News is providing a rundown of what you need to know for the day ahead.

Another exciting day of scientific sessions and Exhibit Hall activities are on the schedule, and this evening, all in-person attendees are invited to the inaugural SABCS^® Celebration. This special event will be held from 8 to 10:30 p.m. CT in the Texas Ballroom of the Grand Hyatt San Antonio Hotel, next to the convention center. The night will be filled with complimentary refreshments and live music, perfect for singing and dancing, courtesy of 1980s New Wave tribute band The Spazmatics. Reconnect with old friends, spend quality time with new acquaintances, and celebrate the SABCS^® community tonight!

In addition, this morning will be the last chance for in-person attendees to participate in the SABCS^® Duck Pluck fundraiser for early-career scientists. Support a good cause and you might win free registration to the 2025 SABCS^®. Stop by the SABCS^® Store in the main lobby before 11 a.m., and make sure to attend Friday afternoon’s View from the Trenches session for the reveal of the winners.

Here are your program highlights for Thursday, December 12, 2024.

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(Full session details can be found in the SABCS® 2024 app, virtual platform, and on SABCS.org.)

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Poster Sessions

Discover top-rated abstracts during five sessions occurring concurrently from 7 to 8:30 a.m. These moderated sessions will include 30 minutes of poster viewing, followed by discussion and panel Q&A periods. This morning’s topics include:

• Session 2: Personalizing CDK4/6 inhibitor therapy for patients with Metastatic Breast Cancer: Survival, QOL, and biomarkers (Hemisfair Ballroom 1-2)
• Session 6: Locoregional Therapy (Room 221ABC)
• Session 8: Novel HER2 Therapeutics (Stars at Night 1-2)
• Session 9: ctDNA uses for Minimal Residual Disease testing, tumor evolution, and novel technologies (Stars at Night 3-4)
• Session 15: Survivorship – Biomarker predictors and other survival-associated factors (Room 221ABC)

An evening block of four sessions will take place from 5:30 to 7 p.m. Those topics will include:

• Session 16: Polygenic Risk (Hemisfair Ballroom 3)
• Session 17: Early Triple-Negative Breast Cancer (Stars at Night 1-2)
• Session 18: Advancing our understanding of invasive lobular carcinoma: Potential to develop personalized therapeutic strategies? (Stars at Night 3-4)
• Session 19: “A penny for your thoughts.” How cost influences care (Hemisfair Ballroom 1-2)

Attendees will have even more opportunities to seek out specific abstracts and hear from the authors during mini oral presentations and special poster viewing periods.

• Rapid Fire 2 (12:15 to 1:05 p.m., Hall 1)
• Poster Session 3 (12:30 to 2 p.m., Exhibit Hall)
• Poster Session 4 (5:30 to 7 p.m., Exhibit Hall)

Plenary Lecture and General Session

Hall 1 is the place to be again this morning, with several hours of unopposed programming beginning at 8:30 a.m.

Melissa Davis, PhD, will deliver the first Plenary Lecture at this year’s Symposium, focusing on the knot of social and biological factors that drive racial disparities in breast cancer outcomes. The second General Session will follow, featuring highly anticipated clinical trial results, including the late-breaking results from the AFT-38 PATINA trial. Check the SABCS^® app and virtual platform for abstract titles and more information.

• Plenary Lecture: The Grand Challenge of Unraveling Social vs Biological Drivers of Racial Disparities in Cancer Outcomes (8:30 to 9 a.m.)
• General Session 2 (9 a.m. to 12:15 p.m.)

Afternoon sessions

Notable topics on this afternoon’s schedule include artificial intelligence, immunotherapy, and risk reduction and early detection. And don’t miss a special American Association for Cancer Research (AACR) award lecture from trailblazing breast cancer researcher Steffi Oesterreich, PhD.

View more details on the app or virtual platform, and watch on-demand recordings of anything you miss.

• Risk Reduction and Early Detection: The Future of Cancer Genetics Is Here (12:30 to 1:45 p.m., Stars at Night 3-4)
• Molecular Tumor Board (1 to 1:50 p.m., Stars at Night 1-2)
• Clinical Controversies: Omission of Axillary Staging in ER-Positive Breast Cancer: Implications on Adjuvant Therapies (2 to 3 p.m., Stars at Night 1-2)
• State of the Art: Revolutionizing Diagnosis and Discovery with Artificial Intelligence (2 to 3 p.m., Stars at Night 3-4)
• AACR Distinguished Lecture in Breast Cancer Research (3 to 3:30 p.m., Stars at Night 1-2)
• Educational Session 9: Artificial Intelligence in the Clinic (3:30 to 5:15 p.m., Stars at Night 3-4)
• Educational Session 10: Immunotherapy (3:30 to 5:15 p.m., Stars at Night 1-2)
• Educational Session 11: Mind the Gap—Breast Cancer in Older Adults (3:30 to 5:15 p.m., Hemisfair Ballroom 3)
• Educational Session 12: The Biology and Treatment Implications of Organ-Specific Metastases (3:30 to 5:15 p.m., Hemisfair Ballroom 1-2)